SND1 Antibody (Center) [APR10966G]

SND1 Antibody (Center) [APR10966G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This SND1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 449-478 amino acids from the Central region of human SND1.

Cellular Localisation: Cytoplasm. Nucleus. Melanosome Note=In IL-4 stimulated cells colocalizes with STAT6 in the nucleus (PubMed:12234934) . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065)

Molecular Weight: 101997

Clone: Polyclonal

Gene Name: SND1

Gene ID: 27044

Function: Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs (PubMed:28546213, PubMed:18453631) . As part of its function in miRNA decay, regulates mRNAs involved in G1-to-S phase transition (PubMed:28546213) . Functions as a bridging factor between STAT6 and the basal transcription factor (PubMed:12234934) . Plays a role in PIM1 regulation of MYB activity (PubMed:9809063) . Functions as a transcriptional coactivator for STAT5 (By similarity) .

Summary: Tissue Location: Ubiquitously expressed.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Staphylococcal nuclease domain-containing protein 1, 100 kDa coactivator, EBNA2 coactivator p100, Tudor domain-containing protein 11, p100 co-activator, SND1, TDRD11