SNX13 polyclonal Antibody | BS72242

SNX13 polyclonal Antibody | BS72242 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB,IF

Application Range: WB 1:500 - 1:2000 IF 1:50 - 1:200

Background: This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha (s), accelerates its GTP hydrolysis, and attenuates G alpha (s) -mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: SNX13 polyclonal Antibody detects endogenous levels of SNX13 protein.

Molecular Weight: 112kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: RGS-PX1

Immunogen: Recombinant protein of human SNX13

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: