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SNX15 polyclonal Antibody | BS71811
- SKU:
- BW-BS71811
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- Usually ships in 5 working days
Description
SNX15 polyclonal Antibody | BS71811 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse
Application: WB,IF
Application Range: WB 1:500 - 1:2000 IF 1:50 - 1:200
Background: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: SNX15 polyclonal Antibody detects endogenous levels of SNX15 protein.
Molecular Weight: 50kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: HSAF001435
Immunogen: Recombinant protein of human SNX15
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: