SOCS7 Polyclonal Antibody | E-AB-12649

SOCS7 Polyclonal Antibody | E-AB-12649 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Ash and phospholipase C gamma-binding protein, NAP 4, NAP 4 Fragment, NAP-4, NAP4, Nck, Nck Ash and phospholipase C binding protein, Nck Ash and phospholipase C gamma binding protein, Nck associated protein 4, Nck-associated protein 4, NCKAP4, SH2 domain containing SOCS box protein, SOCS 7, SOCS-7, SOCS4, SOCS6, Socs7, SOCS7, Suppressor of cytokine signaling 7

Application: IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Signal Transduction

Background: The protein as regulator signaling cascades probably through protein ubiquitination and/or sequestration. It plays an important role in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA.

Concentration: 0.1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human SOCS7

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A