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Sodium tauroursodeoxycholate | B3275

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SKU:
26-B3275-GEN
Availability:
Usually shipped in 5 working days
£776.00 - £1,922.00

Description

Tauroursodeoxycholic acid (TUDCA) is a taurine-conjugated form of the secondary bile acid ursodeoxycholic acid. TUDCA is found in small quantities in human bile but at a higher concentration in the bile of black bears. It acts as an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12.

Tauroursodeoxycholic acid (TUDCA) is a taurine-conjugated form of the secondary bile acid ursodeoxycholic acid. TUDCA is found in small quantities in human bile but at a higher concentration in the bile of black bears. It acts as an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12.

B3275 | Sodium tauroursodeoxycholate DataSheet

Alternate Name/Synonyms: TUDCA 3α,7β-dihydroxy-5β-cholanoyl Taurine 2-[[(3α,5β,7β)-3,7-dihydroxy-24-oxocholan-24-yl]amino]-ethanesulfonic acid, monosodium salt

Appearance:

Formulation:

CAS Number: 35807-85-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₆H₄₄NO₆S • Na

Molecular Weight: 521.69

Cell-Permeable?: True

Purity: ≥98%

Solubilities:

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: An endoplasmic reticulum (ER) stress inhibitor

MDL Number:

PubChem CID: 46782978

SMILES: C[C@H](CCC(NCCS([O-])(=O)=O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])[C@@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C.[Na+]

InChi: InChI=1S/C26H45NO6S.Na/c1-16(4-7-23(30)27-12-13-34(31,32)33)19-5-6-20-24-21(9-11-26(19,20)3)25(2)10-8-18(28)14-17(25)15-22(24)29;/h16-22,24,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33);/q;+1/p-1/t16-,17+,18-,19-,20+,21+,22+,24+,25+,26-;/m1./s1

InChi Key: IYPNVUSIMGAJFC-JUWYWQLMSA-M

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Additional Information

Storage Condition:
-20ºC
Shipping Condition:
Gel Pack
Shelf Life:
36 months
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