SORBS2 Polyclonal Antibody | E-AB-19081

SORBS2 Polyclonal Antibody | E-AB-19081 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Arg binding protein 2, Arg-binding protein 2, Arg/Abl interacting protein 2, Arg/Abl interacting protein, Arg/Abl-interacting protein 2, ArgBP2, KIAA0777, PRO0618, sorbin and SH3 domain containing 2, Sorbin and SH3 domain-containing protein 2, Sorbin, Sorbs2, SRBS2

Application: WB, IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Signal transduction

Background: Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. This gene encodes the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms.

Concentration: 1.02 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human SORBS2

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:1000-1:5000, IHC 1:150-1:300, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 124 kDa

Molecular Weight(Observed): Refer to figures