SORT1 Polyclonal Antibody | E-AB-13686

SORT1 Polyclonal Antibody | E-AB-13686 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: 100 kDa NT receptor, Glycoprotein 95, Gp 95, Gp95, LDLCQ6, Neurotensin receptor 3, NT 3, NT3, NTR 3, NTR3, OTTHUMP00000013784, SORT 1, SORT, SORT1 (gene name), Sort1, Sortilin 1, Sortilin

Application: WB, IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cardiovascular, Metabolism, Neuroscience

Background: This gene encodes a protein that is a multi-ligand type-1 receptor with similarity to the yeast carboxypeptidase Y sorting receptor Vps10 protein. The encoded protein, a trans-Golgi network (TGN) transmembrane protein, binds a number of unrelated ligands that participate in a wide range of cellular processes; however, it lacks the typical features of a signalling receptor. In the TGN, furin mediates the activation of the mature binding form. The encoded protein consists of a large luminal domain, a single transmembrane segment and short C-terminal cytoplasmic tail.

Concentration: 0.7 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human SORT1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:35-1:150

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 92 kDa

Molecular Weight(Observed): N/A