SOS1 Antibody (Center) [APR06135G]

SOS1 Antibody (Center) [APR06135G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This SOS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 934-962 amino acids from the Central region of human SOS1.

Cellular Localisation: N/A

Molecular Weight: 152464

Clone: Polyclonal

Gene Name: SOS1

Gene ID: 6654

Function: Promotes the exchange of Ras-bound GDP by GTP (PubMed:8493579) . Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF (PubMed:17339331) . Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity (By similarity) .

Summary: Tissue Location: Expressed in gingival tissues.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P

Dilution: WB--1:2000

Synonyms: Son of sevenless homolog 1, SOS-1, SOS1