LBD
SOST Antibody (Center) [APR05725G]
- SKU:
- LBD-APR05725G
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Description
SOST Antibody (Center) [APR05725G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This SOST antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-163 amino acids from the Central region of human SOST.
Cellular Localisation: Secreted, extracellular space, extracellular matrix
Molecular Weight: 24031
Clone: Polyclonal
Gene Name: SOST (HGNC:13771)
Gene ID: 50964
Function: Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
Summary: Tissue Location: Widely expressed at low levels with highest levels in bone, cartilage, kidney, liver, bone marrow and primary osteoblasts differentiated for 21 days. Detected in the subendothelial layer of the aortic intima (at protein level) .
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: IHC-P, WB
Dilution: WB--1:1000 IHC-P--1:100~500
Synonyms: Sclerostin, SOST