SOX11 Antibody (N-term) [APR04074G]

SOX11 Antibody (N-term) [APR04074G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, Rat

Specificity: This SOX11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-132 amino acids from the N-terminal region of human SOX11.

Cellular Localisation: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267, ECO:0000269|PubMed:24886874}

Molecular Weight: 46679

Clone: Polyclonal

Gene Name: SOX11

Gene ID: 6664

Function: Transcription factor that acts as a transcriptional activator (PubMed:24886874) . Binds cooperatively with POU3F2/BRN2 or POU3F1/OCT6 to gene promoters, which enhances transcriptional activation (By similarity) . Acts as a transcriptional activator of TEAD2 by binding to its gene promoter and first intron (By similarity) . Plays a redundant role with SOX4 and SOX12 in cell survival of developing tissues such as the neural tube, branchial arches and somites, thereby contributing to organogenesis (By similarity) .

Summary: Tissue Location: Expressed primarily in the brain and heart, with low expression in the kidney, pancreas and muscle

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000 WB--1:1000

Synonyms: Transcription factor SOX-11, SOX11