SOX18 polyclonal Antibody | BS91274

SOX18 polyclonal Antibody | BS91274 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB IHC

Application Range: WB:1:1,000 IHC:1:50-1:200

Background: Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal. Sox-18 is a 384 amino acid nuclear protein that contains one HMG box DNA-binding domain and belongs to the Sox family of transcriptional regulators.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: SOX18 polyclonal Antibody detects endogenous levels of SOX18 protein.

Molecular Weight: 41 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: SOX18, HLTS, SOX 18, Sox18, SOX18, SRY (sex determining region Y) box 18, SRY box 18, Transcription factor SOX 18, Transcription factor SOX-18,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: