Description
SPDEF polyclonal Antibody | BS8406 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB IHC IF
Application Range: WB 1:500 - 1:1000 IHC 1:50 - 1:200 IF 1:50 - 1:100
Background: Prostate epithelium-specific Ets transcription factor (PDEF), also designated prostate Ets or SAM pointed domain containing Ets transcription factor, is a 335 amino acid nuclear protein. PDEF belongs to the Ets family of proteins. This protein, which localizes to prostate epithelial cells, functions as an Ets transcription factor. It upregulates the activity of the p62 promotor but this activity can be downregulated by PSI. It is also involved in the activation of prostate-specific antigen (PSA) by acting as an androgen-independent transactivator.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: SPDEF polyclonal Antibody detects endogenous levels of SPDEF protein.
Molecular Weight: ~ 50 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: SAM pointed domain-containing Ets transcription factor; Prostate epithelium-specific Ets transcription factor; Prostate-specific Ets; Prostate-derived Ets factor; SPDEF; PDEF; PSE
Immunogen: Recombinant full length Human SPDEF.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: