Description
SPDEF Polyclonal Antibody | E-AB-10535 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: bA375E1.3, PDEF, Prostate derived Ets factor, PROSTATE EPITHELIUM SPECIFIC ETS TRANSCRIPTION FACTOR, Prostate epithelium-specific Ets transcription factor, Prostate specific Ets, Prostate-derived Ets factor, Prostate-specific Ets, PSE, RP11-375E1__A.3, SAM POINTED DOMAIN CONTAINING ETS TRANSCRIPTION FACTOR, SAM pointed domain-containing Ets transcription factor, Spdef, SPDEF
Application: IHC, ELISA
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Epigenetics and Nuclear Signaling
Background: The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor-association than other cancer-associated molecules, making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein of human SPDEF
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A