SPG7 Antibody | 13-530

SPG7 Antibody | 13-530 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human SPG7 (NP_003110.1) .

Research Area: Cell Cycle, Neuroscience

Tested Application: WB, IHC

Application: WB: 1:1000 - 1:2000
IHC: 1:50 - 1:200

Specificiy: N/A

Positive Control 1: U-87MG

Positive Control 2: MCF7

Positive Control 3: HT-29

Positive Control 4: K-562

Positive Control 5: Mouse brain

Positive Control 6: Mouse kidney

Molecular Weight: Observed: 88kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: Paraplegin, 3424-, Spastic paraplegia 7 protein, SPG7, CAR, CMAR, PGN

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a mitochondrial metalloprotease protein that is a member of the AAA family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Mutations in this gene cause autosomal recessive spastic paraplegia 7. Two transcript variants encoding distinct isoforms have been identified.