Description
SPG7 monoclonal Antibody | MB65231 | Gentaur UK, US & Europe Distribution
Host: Mouse
Reactivity: Human, Mouse, Rat
Application: FC, IHC, WB
Application Range: WB 1:500, IHC 1:150, FLOW 1:100
Background: This gene encodes a nuclear-encoded mitochondrial metalloprotease protein that is a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Two transcript variants encoding distinct isoforms have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 7. [provided by RefSeq]
Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: SPG7, paraplegin matrix AAA peptidase subunit
Molecular Weight: 88.1 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: CAR; CMAR; PGN; SPG5C
Immunogen: Human recombinant protein fragement corresponding to amino acids 300-573 of human SPG7 (NP_003110) produced in E.coli.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A