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Sphingosine Kinase Inhibitor, SKI-I | 2046
- SKU:
- 26-2046-GEN
- Availability:
- Usually shipped in 5 working days
Description
Cell-permeable. SKI-I is a non-lipid pan-sphingosine kinase (SK) inhibitor that inhibits both SK1 and SK2 to suppress the production of pro-mitogenic sphingosine 1-phosphate (S1P) and promote cell death. Also induces autophagy.
Sphingosine Kinase Inhibitor, SKI-I is a non-lipid pan-sphingosine kinase (SK) inhibitor that inhibits both SK1 and SK2 to suppress the production of pro-mitogenic sphingosine 1-phosphate (S1P) and promote cell death. Also induces autophagy.
2046 | Sphingosine Kinase Inhibitor, SKI-I DataSheet
Alternate Name/Synonyms: 5-naphthalen-2-yl-2H-pyrazole-3-carboxylic acid (2-hydroxy-naphthalen-1-ylmethylene)-hydrazide
Appearance: Pale yellow solid
Formulation: N/A
CAS Number: 306301-68-8
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₅H₁₈N₄O₂
Molecular Weight: 406.44
Cell-Permeable?: Yes
Purity: ≥90% by NMR
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A non-lipid sphingosine kinase (SK) inhibitor
MDL Number: N/A
PubChem CID: N/A
SMILES: O=C(N/N=C/C1C2CCCCC2CCC1O)C3CC(NN3)C4CCC5CCCCC5C4
InChi: InChI=1S/C25H18N4O2/c30-24-12-11-17-6-3-4-8-20(17)21(24)15-26-29-25(31)23-14-22(27-28-23)19-10-9-16-5-1-2-7-18(16)13-19/h1-15,30H,(H,27,28)(H,29,31)/b26-15+
InChi Key: XOXCTLAKMCIWCF-CVKSISIWSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
24 months |