SPNS2 Antibody (N-term) [APR31594G]

SPNS2 Antibody (N-term) [APR31594G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This SPNS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-94 amino acids from the N-terminal region of human SPNS2.

Cellular Localisation: Cell membrane {ECO:0000250|UniProtKB:A2SWM2}; Multi-pass membrane protein. Endosome membrane {ECO:0000250|UniProtKB:A2SWM2}; Multi-pass membrane protein

Molecular Weight: 58044

Clone: Polyclonal

Gene Name: SPNS2 (HGNC:26992)

Gene ID: 124976

Function: Acts a a crucial lysosphingolipid sphingosine 1-phosphate (S1P) transporter involved in S1P secretion and function (PubMed:19074308, PubMed:23180825) . S1P is a bioactive signaling molecule that regulates many physiological processes important for the development and for the immune system. Regulates levels of S1P and the S1P gradient that exists between the high circulating concentrations of S1P and low tissue levels that control lymphocyte trafficking (PubMed:19074308, PubMed:23180825) .

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: IHC-P, WB, FC

Dilution: FC--1:25 WB--1:1000

Synonyms: Protein spinster homolog 2, SPNS2