SPRTN Polyclonal Antibody | E-AB-52495

SPRTN Polyclonal Antibody | E-AB-52495 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: C1orf124, CA124, Chromosome 1 open reading frame 124 , DDDL1880, dJ876B10.3, PRO4323, RP5-876B10.3, Spartan, SprT-like domain at the N terminus, SprT-like N-terminal domain, Zinc finger RAD18 domain-containing protein C1orf124

Application: IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Epigenetics and Nuclear Signaling

Background: The protein encoded by this gene may play a role in DNA repair during replication of damaged DNA. This protein recruits valosin containing protein (p97) to stalled DNA replication forks where it may prevent excessive translesional DNA synthesis and limit the number of DNA-damage induced mutations. It may also be involved in replication-related G2/M-checkpoint regulation. Deficiency of a similar protein in mouse causes chromosomal instability and progeroid phenotypes. Mutations in this gene have been associated with Ruijs-Aalfs syndrome (RJALS). Alternatively spliced transcript variants have been identified.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human SPRTN

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A