SPTAN1 monoclonal Antibody | MB65240

SPTAN1 monoclonal Antibody | MB65240 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: IHC, WB

Application Range: WB 1:500~2000, IHC 1:2000

Background: Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: spectrin alpha, non-erythrocytic 1

Molecular Weight: 47.5 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: EIEE5; NEAS; SPTA2

Immunogen: Human recombinant protein fragment corresponding to amino acids 1-147 of human SPTAN1 (NP_001123910) produced in E.coli.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A