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SPTBN5 polyclonal Antibody | BS61279
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- BW-BS61279
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Description
SPTBN5 polyclonal Antibody | BS61279 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human
Application: WB
Application Range: WB: 1:500~1:1000
Background: Whole-exome sequencing (WES) identified 46 non-synonymous and 13 synonymous somatic single-nucleotide polymorphisms (SNPs) and one frameshift deletion in the coding regions. Specifically, mutations of CDKN2A, TP53, SPTBN5, NOTCH2, and FAM136A were found in the databases. Copy number aberration (CNA) analysis revealed that the cell line loses chromosome 3p and 9p, but lacks amplification of 3q and 11q (as does HPV-negative, smoking-unrelated OTSCC) . It also exhibits four distinctive focal amplifications in chromosome 19p, containing 131 genes without SNPs. Particularly, 52 genes showed >3- to 4-fold amplification and could be potential oncogenic drivers.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: SPTBN5 pAb detects endogenous levels of SPTBN5 protein.
Molecular Weight: ~ 416 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Spectrin beta chain, non-erythrocytic 5; Beta-V spectrin; SPTBN5; BSPECV; HUBSPECV; HUSPECV
Immunogen: Synthetic peptide, corresponding Human SPTBN5.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: