SQSTM1 monoclonal Antibody | MB65241

SQSTM1 monoclonal Antibody | MB65241 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Monkey, Mouse, Rat

Application: FC, IHC, WB

Application Range: WB 1:500~2000, IHC 1:150, FLOW 1:100

Background: This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: sequestosome 1

Molecular Weight: 47.5 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: A170; FTDALS3; OSIL; PDB3; ZIP3; p60; p62; p62B

Immunogen: Full length human recombinant protein of human SQSTM1 (NP_003891) produced in HEK293T cell.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A