SRC monoclonal Antibody | MB65244

SRC monoclonal Antibody | MB65244 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: WB

Application Range: WB 1:500

Background: This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: SRC proto-oncogene, non-receptor tyrosine kinase

Molecular Weight: 59.7 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: ASV; c-SRC; p60-Src; SRC1; THC6

Immunogen: Human recombinant protein fragment corresponding to amino acids 84-365 of human SRC (NP_005408) produced in E.coli.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A