SRMS Antibody (N-term) [AMM07971G]

SRMS Antibody (N-term) [AMM07971G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This SRMS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-48 amino acids from the N-terminal region of human SRMS.

Cellular Localisation: Cytoplasm. Note=Localizes to punctate cytoplasmic structures.

Molecular Weight: 54507

Clone: Polyclonal

Gene Name: SRMS

Gene ID: 6725

Function: Non-receptor tyrosine-protein kinase which phosphorylates DOK1 on tyrosine residues (PubMed:23822091) . Also phosphorylates KHDRBS1/SAM68 and VIM on tyrosine residues (PubMed:29496907) . Phosphorylation of KHDRBS1 is EGF-dependent (PubMed:29496907) .

Summary: Tissue Location: Highly expressed in most breast cancers (at protein level)

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P

Dilution: WB--1:1000 IHC-P--1:100~500

Synonyms: Tyrosine-protein kinase Srms, SRMS, C20orf148