SRPK1 polyclonal Antibody | BS7901

SRPK1 polyclonal Antibody | BS7901 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC IF

Application Range: WB: 1:500~1:2000 IHC: 1:50~1:200 IF: 1:50~1:200

Background: Arginine/serine-rich (RS) domain-containing proteins and their phosphorylation by specific protein kinases constitute control circuits to regulate both constitutive and alternative pre-mRNA splicing and coordinate splicing with transcription in cells. Two SR protein-specific kinases (SRPK, also designated SFRSK), SRPK1 and SRPK2, are highly specific for the phosphorylation of these RS proteins, thereby contributing to splicing regulation. SRPK1 plays a role in the condensation of sperm chromatin. SRPK2 has a stringent preference for SR dipeptides and contains a proline-rich sequence at its amino terminus. Both SRPK1 and SRPK2 are highly expresed in testis. SRPK1 is found exclusively in pancreas and SRPK2 is found exclusively in brain and lung.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: SRPK1 polyclonal Antibody detects endogenous levels of SRPK1 protein.

Molecular Weight: ~ 92 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Serine/arginine rich protein specific kinase 1; Serine/arginine rich splicing factor kinase 1; Serine/arginine-rich protein-specific kinase 1; Serine/threonine protein kinase SRPK1; Serine/threonine-protein kinase SRPK1; SFRS protein kinase 1; SFRSK1; SR protein kinase 1; SR protein specific kinase 1; SR-protein-specific kinase 1; SRPK1; SRPK1_HUMAN;

Immunogen: Recombinant full length Human SRPK1.

Conjugate: N/A

Modification: N/A

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: N/A