SRSF3 Antibody | 8179

SRSF3 Antibody | 8179 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: Predicted species reactivity based on immunogen sequence: Bovine: (100%)

Immunogen: SRSF3 antibody was raised against a 19 amino acid peptide near the center of human SRSF3.
The immunogen is located within amino acids 80 - 130 of SRSF3.

Research Area: Homeostasis, Cancer

Tested Application: E, WB, ICC, IF

Application: SRSF3 antibody can be used for detection of SRSF3 by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunocytochemistry starting at 2 μg/mL. For immunofluorescence start at 2 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Specificiy: SRSF3 antibody is human, mouse and rat reactive.

Positive Control 1: Cat. No. 1204 - K562 Cell Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 18 kDa
Observed: 19 kDa

Validation: N/A

Isoform: N/A

Purification: SRSF3 antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: SRSF3 antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: SRSF3 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: Serine/arginine-rich splicing factor 3, Pre-mRNA-splicing factor SRP20, SFRS3, Splicing factor arginine/serine-rich 3, SRP20

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: SRSF3, a member of the serine/arginine (SR) -rich family of pre-mRNA splicing factors which constitute part of the spliceosome, may be involved in RNA processing in relation with cellular proliferation and/or maturation (1, 2) . Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins (3) . The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation (3, 4) .