SSR128129E | B1165

SSR128129E (SSR) is a potent small molecule, allosteric inhibitor of FGFR signaling. SSR binds to the extracellular part of the receptor and it does not compete with FGF for binding to FGFR but inhibits FGF-induced signaling linked to FGFR internalization in an allosteric manner.

SSR128129E (SSR) is a potent small molecule, allosteric inhibitor of FGFR signaling. SSR binds to the extracellular part of the receptor and it does not compete with FGF for binding to FGFR but inhibits FGF-induced signaling linked to FGFR internalization in an allosteric manner.

B1165 | SSR128129E DataSheet

Alternate Name/Synonyms: 2-Amino-5-(1-methoxy-2-methylindolizine-3-carbonyl)benzoate sodium salt

Appearance: Yellow Solid

Formulation: N/A

CAS Number: 848318-25-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: Yes

Molecular Formula: C₁₈H₁₅N₂NaO₄

Molecular Weight: 346.31

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>30 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: SSR128129E (SSR) is a potent FGFR inhibitor

MDL Number: N/A

PubChem CID: 68853159

SMILES: CC1=C(N2C=CC=CC2=C1OC)C(=O)C3=CC(=C(C=C3)N)C(=O)[O-].[Na+

InChi: 1S/C18H16N2O4.Na/c1-10-15(20-8-4-3-5-14(20)17(10)24-2)16(21)11-6-7-13(19)12(9-11)18(22)23;/h3-9H,19H2,1-2H3,(H,22,23);/q;+1/p-1

InChi Key: JFBMSTWZURKQOC-UHFFFAOYSA-M