Description
STAT6 Polyclonal Antibody | E-AB-10059 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: 12S1644, D12S1644, IL 4 STAT, IL-4 Stat, IL4 STAT, Interleukin 4 Induced, Interleukin 4 Induced Transcription Factor IL4 STAT, Signal transducer and activator of transcription 6, Signal Transducer And Activator Of Transcription 6 Interleukin 4 Induced, Signal Transducer And Activator Of Transcription 6 Nirs Variant 1, Signal transducer and activator of transcription 6, interleukin 4 induced, STAT 6, STAT interleukin4 induced, STAT, interleukin4 induced, Stat6, STAT6, STAT6B, STAT6C, Transcription factor IL 4 STAT
Application: WB, ELISA
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction
Background: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.
Concentration: 0.2 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein of human STAT6
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 94 kDa
Molecular Weight(Observed): N/A