STING Inhibitor, C-176 | B2341

STING inhibitor C-176 is a potent, small-molecule inhibitor of STING (stimulator of interferon genes) protein, that attenuates STING-associated autoinflammatory disease in mice. STING protein is a central signaling component of the intracellular DNA sensing pathway.

STING inhibitor C-176 is a potent, small-molecule inhibitor of STING (stimulator of interferon genes) protein, that attenuates STING-associated autoinflammatory disease in mice. STING protein is a central signaling component of the intracellular DNA sensing pathway.

B2341 | STING Inhibitor, C-176 DataSheet

Alternate Name/Synonyms: N-(4-iodophenyl)-5-nitrofuran-2-carboxamide,C-176,C176

Appearance: Crystalline solid

Formulation:

CAS Number: 314054-00-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₁₁H₇IN₂O₄

Molecular Weight: 358.09

Cell-Permeable?: TRUE

Purity: ≥98% by HPLC

Solubilities: >5 mg/ml (DMSO)

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A potent STING inhibitor

MDL Number:

PubChem CID: 103958

SMILES: C1=CC(=CC=C1NC(=O)C2=CC=C(O2)[N+](=O)[O-])I

InChi: InChI=1S/C11H7IN2O4/c12-7-1-3-8(4-2-7)13-11(15)9-5-6-10(18-9)14(16)17/h1-6H,(H,13,15)

InChi Key: JBIKQXOZLBLMKI-UHFFFAOYSA-N