STIP1 polyclonal Antibody | BS91297

STIP1 polyclonal Antibody | BS91297 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB IHC FC IP ICC

Application Range: WB:1:500-1:1,000 IHC:1:50-1:200 FC:1:50-1:100 ICC:1:50

Background: Stress-induced-phosphoprotein 1 (STI1) functions as a co-chaperone for HSP70 and HSP90 during heat shock response. STI1 exists as either a monomer or a dimer, and this conformational flexibility facilitates its function in organizing HSP70/HSP90. HSP90 acts as an ATPase, and requires the recruitment of client proteins and proper conformation to function. STI1 acts as a "scaffold" for client protein recruitment to the relaxed, ADP-bound conformation of HSP90, thus suppressing ATP turnover during the loading phase and allowing proper function.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: STIP1 polyclonal Antibody detects endogenous levels of STIP1 protein.

Molecular Weight: 63 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: STI1, Hop, STIP1, Epididymis secretory sperm binding protein Li 94n, HEL S 94n, Hop, Hsc70/Hsp90 organizing protein, Hsc70/Hsp90-organizing protein, IEF SSP 3521, NY REN 11 antigen, P60, Renal carcinoma antigen NY-REN-11, STI1, STI1L, STIP1, STIP1, Stress induced phosphoprotein 1, Stress-induced-phosphoprotein 1, Transformation sensitive protein IEF SSP 3521, Transformation-sensitive protein IEF SSP 3521,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: