STMN2 Antibody (Center) [APR33046G]

STMN2 Antibody (Center) [APR33046G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This STMN2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 82-116 amino acids from the Central region of human STMN2.

Cellular Localisation: Cytoplasm. Cytoplasm, perinuclear region. Cell projection, growth cone. Membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, axon. Golgi apparatus. Endosome. Cell projection, lamellipodium. Note=Associated with punctate structures in the perinuclear cytoplasm, axons, and growth cones of developing neurons. SCG10 exists in both soluble and membrane- bound forms. Colocalized with CIB1 in neurites of developing hippocampal primary neurons (By similarity) . Colocalized with CIB1 in the cell body, neuritis and growth cones of neurons. Colocalized with CIB1 to the leading edge of lamellipodia.

Molecular Weight: 20828

Clone: Polyclonal

Gene Name: STMN2

Gene ID: 11075

Function: Regulator of microtubule stability. When phosphorylated by MAPK8, stabilizes microtubules and consequently controls neurite length in cortical neurons. In the developing brain, negatively regulates the rate of exit from multipolar stage and retards radial migration from the ventricular zone (By similarity) .

Summary: Tissue Location: Neuron specific.

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB, IHC, IF, FC

Dilution: FC--1:25 IF--1:25 IHC--1:100~500 WB--1:1000

Synonyms: Stathmin-2, Superior cervical ganglion-10 protein, Protein SCG10, STMN2, SCG10, SCGN10