STOM Antibody (N-term) [APR13585G]

STOM Antibody (N-term) [APR13585G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This STOM antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 2-36 amino acids from the N-terminal region of human STOM.

Cellular Localisation: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell membrane; Lipid-anchor; Cytoplasmic side. Membrane raft. Melanosome. Cytoplasmic vesicle {ECO:0000250|UniProtKB:P54116}. Note=Localizes to juxtanuclear structure probably derived from the Golgi apparatus (PubMed:9243190) Colocalizes with cortical actin microfilaments at small plasma membrane protrusions (PubMed:9243190) . Associates with alpha-granular lipid rafts (PubMed:12130500) . Translocates from the alpha-granular lipid rafts to the cell membrane on thrombin activation and selectively enriched in released microvesicles (PubMed:12130500) . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545) .

Molecular Weight: 31731

Clone: Polyclonal

Gene Name: STOM (HGNC:3383)

Gene ID: 2040

Function: Regulates ion channel activity and transmembrane ion transport. Regulates ASIC2 and ASIC3 channel activity.

Summary: Tissue Location: Detected in erythrocytes (at protein level) . Widely expressed.

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Erythrocyte band 7 integral membrane protein, Protein 72b, Stomatin, STOM, BND7, EPB72