STX1A monoclonal Antibody | MB65287

STX1A monoclonal Antibody | MB65287 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: IF, WB

Application Range: WB 1:500, IF 1:100

Background: This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein) -Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc) . Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: syntaxin 1A

Molecular Weight: 33 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: HPC-1; P35-1; STX1; SYN1A

Immunogen: Full length human recombinant protein of human STX1A (NP_004594) produced in E.coli.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A