STXBP1 polyclonal Antibody | BS62093

STXBP1 polyclonal Antibody | BS62093 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rabbit

Application: WB

Application Range: WB: 1:500~1:1000

Background: Munc18-1 belongs to the Munc18 protein family that also includes Munc18-2 and Munc18-3. These proteins are highly conserved at the amino acid sequence level and play a critical role in membrane fusion. Munc18 proteins control SNARE complex formation and interact with syntaxin. In Munc18-1 knockout mice, neurotransmitter release is completely abolished. In addition, Munc18-1 acts as a molecular chaperone for syntaxin-1, allowing for formation of the SNARE complex at the plasma membrane. Munc18-1 also acts as a regulator of vesicle docking during exocytosis.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: STXBP1 polyclonal Antibody detects endogenous levels of STXBP1 protein.

Molecular Weight: ~ 70kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Syntaxin-binding protein 1; MUNC18-1; N-Sec1; N-Sec1;Protein unc-18 homolog 1; Unc18-1; Protein unc-18 homolog A; Unc-18A; p67; STXBP1; UNC18A

Immunogen: Synthetic peptide, corresponding to Human STXBP1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: