Description
SUMO4 Polyclonal Antibody | E-AB-60839 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: SUMO4, IDDM5, SMT3H4, SUMO-4, dJ281H8.4
Application: WB, IHC
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling
Background: This gene is a member of the SUMO gene family. This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteins' subcellular localization, stability, or activity. The protein described in this record is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. A specific polymorphism in this SUMO gene, which leads to the M55V substitution, has been associated with type I diabetes. The RefSeq contains this polymorphism.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: A synthetic peptide of human SUMO4
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Method: Affinity purification
Dilution: WB 1:1000-1:2000 IHC 1:100-1:300
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 10 kDa
Molecular Weight(Observed): 18 kDa