223

SuperKillerTRAIL, Soluble Recombinant Protein | 90-336

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SKU:
223-90-336-GEN
NULL917.00

Description

SuperKillerTRAIL, Soluble Recombinant Protein | 90-336 | Gentaur UK, US & Europe Distribution

Tested Application: N/A

Application: This recombinant proteins is for research use only.

Tpredicted Molecular Weight: N/A

Physical State: Liquid

Buffer: In 20mM HEPES, pH 7.4, 150mM NaCl, 0.005% Tween 20, 1% sucrose, 1mM DTT.

Storage Condition: Once thawed it is recommended to prepare appropriate aliquots and to store them at -80˚C.

Alternate Name: TRAIL, Apo-2L, TNFSF10, CD253

Background: N/A

Shipping: Dry Ice

Disclaimer: Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

Source: E. coli

Species: Human

By Source: E. Coli

By Species: Human

Fusion Tag: His Tag

Sequence: The extracellular domain of human TRAIL (aa 95-281) is fused at the N-terminus to a His-tag and a linker peptide. The active multimeric conformation is stabilized by an inserted mutation allowing an additional CC-bridge.

Bological Activity: Induces apoptosis at concentrations of >1ng/ml. Note: Does not require a cross-linking enhancer for its potent biological activity. Shows superior activity on human cell lines that require extensive cross-linking of TRAIL-Rs for killing (e.g. Jurkat).

Purity: >98% (SDS-PAGE).

Endotoxin level is less than 0.01EU/ μg purified protein (LAL test; Lonza).

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Additional Information

Size:
20 ug
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