Description
SuperKillerTRAIL, Soluble Recombinant Protein | 90-336 | Gentaur UK, US & Europe Distribution
Tested Application: N/A
Application: This recombinant proteins is for research use only.
Tpredicted Molecular Weight: N/A
Physical State: Liquid
Buffer: In 20mM HEPES, pH 7.4, 150mM NaCl, 0.005% Tween 20, 1% sucrose, 1mM DTT.
Storage Condition: Once thawed it is recommended to prepare appropriate aliquots and to store them at -80˚C.
Alternate Name: TRAIL, Apo-2L, TNFSF10, CD253
Background: N/A
Shipping: Dry Ice
Disclaimer: Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Source: E. coli
Species: Human
By Source: E. Coli
By Species: Human
Fusion Tag: His Tag
Sequence: The extracellular domain of human TRAIL (aa 95-281) is fused at the N-terminus to a His-tag and a linker peptide. The active multimeric conformation is stabilized by an inserted mutation allowing an additional CC-bridge.
Bological Activity: Induces apoptosis at concentrations of >1ng/ml. Note: Does not require a cross-linking enhancer for its potent biological activity. Shows superior activity on human cell lines that require extensive cross-linking of TRAIL-Rs for killing (e.g. Jurkat).
Purity: >98% (SDS-PAGE).
Endotoxin level is less than 0.01EU/ μg purified protein (LAL test; Lonza).