SUPV3L1 polyclonal Antibody | BS71382

SUPV3L1 polyclonal Antibody | BS71382 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: WB,IHC,IF

Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Background: SUV3, also known as SUPV3L1 (suppressor of var1, 3-like 1), is a 786 amino acid protein that localizes to both the nucleus and the mitochondrial matrix and contains one helicase C-terminal domain, as well as one helicase ATP-binding domain. Expressed in a broad range of tissues, SUV3 interacts with HBXIP and functions as an ATPase DNA/RNA helicase that uses magnesium as a cofactor to catalyze the unwinding of DNA/RNA and RNA/RNA duplexes, thereby playing a role in DNA replication and transcriptional initiation. SUV3 exhibits optimal activity at a pH of 5 and, in addition to its helicase activity, is thought to protect cells from apoptosis and participate in maintaining mitochondrial homeostasis.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: SUPV3L1 polyclonal Antibody detects endogenous levels of SUPV3L1 protein.

Molecular Weight: ~ 88 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: SUV3; SUV3-like protein 1

Immunogen: Recombinant protein of human SUPV3L1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: