Survivin Antibody | 3170

Survivin is a newly described apoptosis inhibitor that is expressed in many human cancers, but undetectable in terminally differentiated adult tissues. It has been shown that recombinant expression of Survivin counteracts apoptosis of B lymphocyte precursors deprived of interleukin 3 (IL-3), s?ggesting a potential role of Survivin in cancer therapy. Survivin is expressed in G2-M phase in a cell cycle-dependent manner and directly associated with mitotic spindle microtubules, s?ggesting a role in both apoptosis regulation and cell cycle progression.

3170 | Survivin Antibody DataSheet

Antibody Target: Survivin/TIAP

Target Alternative Name: BIRC5, IAP4 , API4, SVV , EPR-1

Tag Line:

Category: Surivivn

Host: Rabbit

Isotype: Rabbit IgG

Species Reactivities: Human

Immunogen Sequence: Recombinant human survivin

Accession #: O15392

Gene ID: 332

Appearance: Colorless liquid

Form: Liquid

Concentration: 0.5 mg/ml

Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit anti-Survivin polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.

Purification: Affinity purified

Application: Western blot

Positive Control: Recombinant human Survivin (Cat.# 4160-10)

Application And Usages: Western blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually.

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: Verified

Immunocytochemistry Verified: Not Verified

Immunofluorescence Verified: Not Verified

Immunoprecipitation Verified: Not Verified

FACS Verified:

ELISA Verified: Not Verified

ChIP Verified: Not Verified

Dot Blot Verified:

Flow Cytometry Verified: Not Verified