SUSD2 Antibody (C-term) [APR03769G]

SUSD2 Antibody (C-term) [APR03769G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This SUSD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 716-745 amino acids from the C-terminal region of human SUSD2.

Cellular Localisation: Cell membrane; Single-pass type I membrane protein. Note=SUSD2 and LGALS1 co-localized in very specific, punctate regions along the cell membrane of breast cancer cells

Molecular Weight: 90208

Clone: Polyclonal

Gene Name: SUSD2

Gene ID: 56241

Function: May be a cytokine receptor for C10ORF99. May be a tumor suppressor; together with C10ORF99 has a growth inhibitory effect on colon cancer cells which includes G1 cell cycle arrest (PubMed:25351403) . May play a role in breast tumorigenesis (PubMed:23131994) .

Summary: Tissue Location: Highly expressed in breast cancer, but shows a restricted expression pattern in normal tissues such as adipose, adrenal gland, kidney, lung, mammary gland, placenta, thyroid, trachea, and uterus (PubMed:23131994) . Also expressed in colon; down-regulated in colon cancer tissues (PubMed:25351403)

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: IHC-P, WB

Dilution: WB--1:1000 IHC-P--1:100~500

Synonyms: Sushi domain-containing protein 2, SUSD2