SYAP1 Antibody (C-term) [APR04202G]

SYAP1 Antibody (C-term) [APR04202G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This SYAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-238 amino acids from the C-terminal region of human SYAP1.

Cellular Localisation: Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q9D5V6}. Golgi apparatus {ECO:0000250|UniProtKB:Q9D5V6}. Perikaryon {ECO:0000250|UniProtKB:Q9D5V6}. Cell projection, axon {ECO:0000250|UniProtKB:Q9D5V6}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q9D5V6}. Cell projection, growth cone {ECO:0000250|UniProtKB:Q9D5V6}. Cell junction, synapse, presynaptic cell membrane {ECO:0000250|UniProtKB:Q9D5V6}. Cell junction, synapse, postsynaptic cell membrane {ECO:0000250|UniProtKB:Q9D5V6}. Membrane. Note=Localizes to cholinergic neuromuscular junctions and in actin-rich growth cone regions (By similarity) . Membrane-associated in a epidermal growth factor (EGF) - dependent manner (PubMed:23300339) . {ECO:0000250|UniProtKB:Q9D5V6, ECO:0000269|PubMed:23300339}

Molecular Weight: 39933

Clone: Polyclonal

Gene Name: SYAP1 (HGNC:16273)

Gene ID: 94056

Function: Plays a role in adipocyte differentiation by promoting mTORC2-mediated phosphorylation of AKT1 at 'Ser-473' after growth factor stimulation (PubMed:23300339) .

Summary: Tissue Location: Expressed in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas (PubMed:23300339)

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Synapse-associated protein 1, SYAP1