LBD
Synphilin-1 (SNCAIP) Antibody (C-term) [APR13635G]
- SKU:
- LBD-APR13635G
- Availability:
- Usually ships in 5 working days
Description
Synphilin-1 (SNCAIP) Antibody (C-term) [APR13635G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H, M
Specificity: This Synphilin-1 (SNCAIP) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 593-622 amino acids from the C-terminal region of human Synphilin-1 (SNCAIP) .
Cellular Localisation: Cytoplasm. Note=Detected in cytoplasmic inclusion bodies, together with SNCA
Molecular Weight: 100409
Clone: Polyclonal
Gene Name: SNCAIP
Gene ID: 9627
Function: Isoform 2 inhibits the ubiquitin ligase activity of SIAH1 and inhibits proteasomal degradation of target proteins. Isoform 2 inhibits autoubiquitination and proteasomal degradation of SIAH1, and thereby increases cellular levels of SIAH. Isoform 2 modulates SNCA monoubiquitination by SIAH1.
Summary: Tissue Location: Detected in brain (at protein level) . Widely expressed, with highest levels in brain, heart and placenta
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Synphilin-1, Sph1, Alpha-synuclein-interacting protein, SNCAIP