Synphilin-1 (SNCAIP) Antibody (C-term) [APR13635G]

Synphilin-1 (SNCAIP) Antibody (C-term) [APR13635G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This Synphilin-1 (SNCAIP) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 593-622 amino acids from the C-terminal region of human Synphilin-1 (SNCAIP) .

Cellular Localisation: Cytoplasm. Note=Detected in cytoplasmic inclusion bodies, together with SNCA

Molecular Weight: 100409

Clone: Polyclonal

Gene Name: SNCAIP

Gene ID: 9627

Function: Isoform 2 inhibits the ubiquitin ligase activity of SIAH1 and inhibits proteasomal degradation of target proteins. Isoform 2 inhibits autoubiquitination and proteasomal degradation of SIAH1, and thereby increases cellular levels of SIAH. Isoform 2 modulates SNCA monoubiquitination by SIAH1.

Summary: Tissue Location: Detected in brain (at protein level) . Widely expressed, with highest levels in brain, heart and placenta

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Synphilin-1, Sph1, Alpha-synuclein-interacting protein, SNCAIP