SYNPO Antibody (C-term) [APR14254G]

SYNPO Antibody (C-term) [APR14254G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This SYNPO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 654-683 amino acids from the C-terminal region of human SYNPO.

Cellular Localisation: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q8CC35}. Cell junction, tight junction {ECO:0000250|UniProtKB:Q8CC35}. Perikaryon {ECO:0000250|UniProtKB:Q8CC35}. Cell projection, dendritic spine {ECO:0000250|UniProtKB:Q8CC35}. Cell junction, synapse, postsynaptic density {ECO:0000250|UniProtKB:Q8CC35}. Cell junction, synapse {ECO:0000250|UniProtKB:Q8CC35}. Cytoplasm, cytosol. Note=Localized at the tight junction of cells. In brain, localized to the postsynaptic densities and in the perikarya. Associated with dendritic spines of a subset of synapses {ECO:0000250|UniProtKB:Q8CC35}

Molecular Weight: 99463

Clone: Polyclonal

Gene Name: SYNPO

Gene ID: 11346

Function: Actin-associated protein that may play a role in modulating actin-based shape and motility of dendritic spines and renal podocyte foot processes. Seems to be essential for the formation of spine apparatuses in spines of telencephalic neurons, which is involved in synaptic plasticity (By similarity) .

Summary: Tissue Location: Expressed in cerebral cortex.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Synaptopodin, SYNPO, KIAA1029