BW
Synuclein-β (S118) polyclonal Antibody | BS1348
- SKU:
- BW-BS1348
- Availability:
- Usually ships in 5 working days
Description
Synuclein-β (S118) polyclonal Antibody | BS1348 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB IHC IF
Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
Background: The synuclein family members, including α-synuclein (also designated NACP for non-β amyloid component) and β-synuclein, are predominantly expressed in the brain and are speculated to be involved in synaptic regulation and neuronal plasticity. α-synuclein is localized to neuronal cell bodies and synapses. α-synuclein was first identified as a component of Alzheimer’s disease amyloid plaques. Abnormal platelet function in Alzheimer’s disease has been demonstrated. During megakaryocytic differentiation α-synuclein was found to be upregulated, while β-synuclein is downregulated, indicating that coordinate expression of synucleins may be important during hematopoetic cell differentiation. A mutant form of α-synuclein has been found in patients with early onset Parkinson’s disease.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Synuclein β (S118) polyclonal Antibody detects endogenous levels of Synuclein β protein.
Molecular Weight: ~ 14 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Beta-synuclein; SNCB; Synuclein β; β-Synuclein
Immunogen: Synthetic peptide, corresponding to amino acids 82-140 of Human Synuclein-β.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: