TAB3 Polyclonal Antibody | E-AB-11380

TAB3 Polyclonal Antibody | E-AB-11380 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: MAP3K7IP 3, Mitogen-activated protein kinase kinase kinase 7-interacting protein 3, NAP1, NF-kappa-B-activating protein 1, NFkB activating protein 1, TAB-3, Tab3, TAB3, TAK1 binding protein 3, TAK1-binding protein 3, TGF-beta-activated kinase 1 and MAP3K7-binding protein 3, TGF-beta-activated kinase 1-binding protein 3

Application: WB, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Epigenetics and Nuclear Signaling, Immunology, Signal Transduction

Background: The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene.

Concentration: 0.2 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human TAB3

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:1000-1:5000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 79 kDa

Molecular Weight(Observed): N/A