TADA3L polyclonal Antibody | BS7973

TADA3L polyclonal Antibody | BS7973 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB,IF

Application Range: WB 1:500 - 1:2000 IF 1:50 - 1:200

Background: ADA3 (Transcriptional adapter 3-like, STAF54) is a 432 amino acid protein encoded by the human gene TADA3L. ADA3 is a ubiquitously expressed nuclear protein that functions as a component of the PCAF (p300/CBP-associated factor) complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex is the human homolog of the yeast SAGA complex. ADA3 interacts with the E6 gene and is a target of E6-induced degradation. ADA3 binds selectively to the high-risk HPV E6 proteins and immortalization-competent E6 mutants. ADA3 functions as a coactivator for p53-mediated transactivation by stabilizing p53 protein.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: TADA3L polyclonal Antibody detects endogenous levels of TADA3L protein.

Molecular Weight: ~ 55 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: ADA3; ADA3 homolog; ADA3-like protein; FLJ20221; FLJ21329; hADA3; Transcriptional adaptor 3 (NGG1 homolog yeast) like; Transcriptional adaptor 3 like;

Immunogen: Recombinant full length Human TADA3L.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: