Description
TAF12 polyclonal Antibody | BS7773 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB
Application Range: WB: 1:500~1:2000
Background: TFIID is a general transcription factor that initiates preinitiation complex assembly through direct interaction with the TATA promoter element. Functioning as a multisubunit complex consisting of a small TATA-binding polypeptide and other TBP-associated factors (TAFs), TFIID mediates promoter responses to various transcriptional activators and repressors. TAF II p20, also known as TAF12, TAF15, TAF2J or TAFII20, is a 161 amino acid subunit of TFIID that localizes to the nucleus and contains one histone-fold domain. Expressed ubiquitously, TAF II p20 interacts with other members of the TFIID complex and, via this interaction, plays a role in mediating transcriptional activation and repression. Two isoforms of TAF II p20 exist due to alternative splicing events.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: TAF12 polyclonal Antibody detects endogenous levels of TAF12 protein.
Molecular Weight: ~ 18 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: TAF12 RNA polymerase II, TATA box binding protein (TBP) -associated factor, 20kDa; TAF15; TAF2J; TAFII 20/TAFII 15; TAFII20; TAFII20/TAFII15; Transcription initiation factor TFIID 20/15 kDa subunits; Transcription initiation factor TFIID subunit 12;
Immunogen: Recombinant full length Human TAF12.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: PI3K AKT signaling,G Protein-coupled Receptors Signaling to MAPK Erk,Cell Cycle G2 M DNA Damage Signaling Pathway,MAPK Erk in Growth and Differentiation Pathway,