Description
TANK monoclonal Antibody | MB65331 | Gentaur UK, US & Europe Distribution
Host: Mouse
Reactivity: Human, Rat
Application: IHC, WB
Application Range: WB 1:500~2000, IHC 1:500
Background: The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: TRAF family member associated NFKB activator
Molecular Weight: 47.6 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: I-TRAF; ITRAF; TRAF2
Immunogen: Full length human recombinant protein of human TANK (NP_004171) produced in HEK293T cell.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A