TAPBP polyclonal Antibody | BS7411

TAPBP polyclonal Antibody | BS7411 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC IF

Application Range: WB: 1:500~1:2000 IHC/IF: 1:50~1:200

Background: This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: TAPBP polyclonal Antibody detects endogenous levels of TAPBP protein.

Molecular Weight: ~47 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: NGS 17; NGS-17; NGS17; TAP associated protein; TAP binding protein; TAP binding protein (tapasin) ; TAP BP; TAP-associated protein; TAP-binding protein; TAPA; Tapasin; TAPBP; TPN; TPSN; TPSN_HUMAN;

Immunogen: Recombinant full length Human TAPBP.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: