TARDBP Antibody | 14-156

TARDBP Antibody | 14-156 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human TARDBP (NP_031401.1) .

Research Area: Apoptosis, Cell Cycle, Neuroscience

Tested Application: WB, IHC, IF, IP, RIP

Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:100
IF: 1:20 - 1:100
IP: 1:50 - 1:100
RIP: 1:20 - 1:50

Specificiy: N/A

Positive Control 1: HeLa

Positive Control 2: Jurkat

Positive Control 3: SW620

Positive Control 4: HT-29

Positive Control 5: A-673

Positive Control 6: Es-2

Molecular Weight: Observed: 42kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: TDP43 Antibody: ALS10, TDP-43, TDP43, TAR DNA-binding protein 43

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS) , contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.